Federico Pea Selected Research

Meropenem (Merrem)

1/2022	Successful Treatment of Bacteremia and Ventilator-Associated Pneumonia Caused by KPC/OXA-48-like Klebsiella pneumoniae Co-Producer with a Continuous Infusion of High-Dose Meropenem Plus Fosfomycin Guided by Real-Time Therapeutic Drug Monitoring.
1/2021	Impact of Maximizing Css/MIC Ratio on Efficacy of Continuous Infusion Meropenem Against Documented Gram-Negative Infections in Critically Ill Patients and Population Pharmacokinetic/Pharmacodynamic Analysis to Support Treatment Optimization.
10/2020	Real-time TDM-based optimization of continuous-infusion meropenem for improving treatment outcome of febrile neutropenia in oncohaematological patients: results from a prospective, monocentric, interventional study.
8/2020	Population Pharmacokinetics of Continuous-Infusion Meropenem in Febrile Neutropenic Patients with Hematologic Malignancies: Dosing Strategies for Optimizing Empirical Treatment against Enterobacterales and P. aeruginosa.
10/2019	Use of meropenem in treating carbapenem-resistant Enterobacteriaceae infections.
8/2018	Higher than standard meropenem and linezolid dosages needed for appropriate treatment of an intracerebral hemorrhage patient with augmented renal clearance.
10/2017	Population Pharmacokinetics of High-Dose Continuous-Infusion Meropenem and Considerations for Use in the Treatment of Infections Due to KPC-Producing Klebsiella pneumoniae.
2/2017	Might real-time pharmacokinetic/pharmacodynamic optimisation of high-dose continuous-infusion meropenem improve clinical cure in infections caused by KPC-producing Klebsiella pneumoniae?
9/2015	Pharmacokinetics and pharmacodynamics of continuous-infusion meropenem in pediatric hematopoietic stem cell transplant patients.
9/2015	Pharmacokinetics and pharmacodynamics of continuous infusion meropenem in overweight, obese, and morbidly obese patients with stable and unstable kidney function: a step toward dose optimization for the treatment of severe gram-negative bacterial infections.

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Federico Pea Research Topics

Disease

57	Infections 08/2022 - 04/2003
35	Critical Illness (Critically Ill) 03/2022 - 11/2002
9	Pneumonia (Pneumonitis) 08/2020 - 06/2006
8	COVID-19 02/2022 - 08/2020
7	Ventilator-Associated Pneumonia 01/2022 - 01/2003
7	Sepsis (Septicemia) 12/2021 - 01/2005
5	Bacterial Infections (Bacterial Infection) 05/2021 - 12/2009
5	Communicable Diseases (Infectious Diseases) 01/2021 - 10/2010
5	Endocarditis 01/2021 - 09/2011
5	Wounds and Injuries (Trauma) 01/2020 - 12/2002
4	Neoplasms (Cancer) 10/2022 - 08/2014
4	Bacteremia 01/2022 - 08/2009
4	Febrile Neutropenia 10/2020 - 01/2004
4	Thrombocytopenia (Thrombopenia) 12/2019 - 08/2012
4	Bacterial Meningitis 02/2016 - 10/2003
3	Invasive Fungal Infections 10/2022 - 11/2018
3	Osteomyelitis 01/2021 - 11/2017
3	Invasive Candidiasis 08/2020 - 01/2018
3	Aspergillosis 10/2019 - 11/2008
3	Candidiasis (Moniliasis) 08/2019 - 10/2013
3	Staphylococcal Infections 01/2018 - 02/2015
3	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018 - 01/2003
3	Drug-Related Side Effects and Adverse Reactions 12/2016 - 11/2008
3	Meningitis 02/2016 - 05/2007
3	Renal Insufficiency (Renal Failure) 07/2011 - 08/2006
3	Cross Infection (Nosocomial Infection) 10/2010 - 04/2007
2	Septic Shock (Toxic Shock Syndrome) 10/2021 - 01/2009
2	Central Nervous System Infections (Central Nervous System Infection) 05/2018 - 11/2017
2	Diabetic Foot 05/2018 - 11/2017
2	Overweight 01/2018 - 09/2015
2	Chronic Renal Insufficiency 01/2018 - 01/2017
2	Morbid Obesity 12/2016 - 07/2011
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2013 - 08/2005
1	Pain (Aches) 01/2022
1	Hemorrhage 01/2022
1	Cancer Pain 01/2022
1	Mycoses (Diseases, Fungus) 12/2021
1	Disease Progression 12/2021

Drug/Important Bio-Agent (IBA)

46	Pharmaceutical PreparationsIBA 01/2022 - 11/2002
22	Anti-Bacterial Agents (Antibiotics)IBA 08/2022 - 01/2003
13	Meropenem (Merrem)FDA LinkGeneric 01/2022 - 07/2011
11	Linezolid (Zyvox)FDA Link 01/2020 - 12/2004
11	Vancomycin FDA LinkGeneric 01/2020 - 11/2002
10	Levofloxacin (Levaquin)FDA Link 01/2017 - 01/2003
7	beta-LactamsIBA 12/2021 - 10/2003
6	Voriconazole (Vfend)FDA LinkGeneric 10/2022 - 11/2008
6	Carbapenems (Carbapenem Antibiotics)IBA 01/2022 - 09/2015
6	dalbavancinIBA 11/2021 - 01/2020
6	TeicoplaninIBA 09/2020 - 04/2003
6	FluoroquinolonesIBA 01/2018 - 01/2005
5	CreatinineIBA 01/2018 - 05/2009
5	Anti-Infective Agents (Microbicides)IBA 11/2014 - 01/2007
4	CefiderocolIBA 12/2021 - 01/2020
4	carbapenemaseIBA 12/2021 - 12/2012
4	ceftobiproleIBA 10/2021 - 12/2016
4	Fluconazole (Zonal)FDA LinkGeneric 08/2020 - 09/2014
4	GlycopeptidesIBA 05/2018 - 01/2005
4	Daptomycin FDA Link 01/2017 - 07/2011
3	isavuconazoleIBA 10/2022 - 10/2019
3	Fosfomycin FDA Link 01/2022 - 02/2021
3	ceftazidime drug combination avibactamIBA 01/2022 - 10/2021
3	tazobactam drug combination ceftolozaneIBA 12/2021 - 04/2018
3	AminoglycosidesIBA 01/2020 - 01/2005
3	Rifampin (Rifampicin)FDA LinkGeneric 01/2018 - 01/2005
2	beta-Lactamase InhibitorsIBA 12/2021 - 05/2021
2	AzolesIBA 12/2021 - 10/2013
2	Antiviral Agents (Antivirals)IBA 12/2021 - 01/2020
2	Monoclonal AntibodiesIBA 12/2021 - 08/2014
2	EchinocandinsIBA 11/2021 - 10/2013
2	Antifungal AgentsIBA 11/2021 - 08/2020
2	ProcalcitoninIBA 01/2021 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
2	tocilizumab (atlizumab)FDA Link 12/2020 - 08/2020
2	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2020 - 12/2016
2	Ceftazidime (Fortum)FDA LinkGeneric 01/2019 - 08/2005
2	Valganciclovir FDA Link 11/2018 - 12/2017
2	SteroidsIBA 11/2018 - 09/2015
2	posaconazole FDA Link 11/2018 - 12/2013
2	Proton Pump InhibitorsIBA 11/2018 - 12/2013
2	MacrolidesIBA 01/2018 - 01/2005
2	TetracyclinesIBA 01/2018 - 01/2005
1	Factor XIII (Coagulation Factor XIII)IBA 01/2022
1	Opioid Analgesics (Opioids)IBA 01/2022
1	ElementsIBA 01/2022
1	TriazolesIBA 12/2021
1	Tigecycline (Tygacil)FDA Link 12/2021
1	AnticoagulantsIBA 12/2021

Therapy/Procedure

43	Therapeutics 08/2022 - 11/2002
6	Liver Transplantation 11/2021 - 01/2009
4	Continuous Renal Replacement Therapy 10/2021 - 12/2004
4	Drug Therapy (Chemotherapy) 01/2020 - 01/2004
3	Critical Care (Surgical Intensive Care) 01/2021 - 01/2018
2	Mechanical Ventilators (Ventilator) 03/2022 - 12/2021
2	Drug Tapering 01/2019 - 01/2018
2	Hematopoietic Stem Cell Transplantation 11/2018 - 12/2017
2	Induction Chemotherapy 11/2018 - 12/2013
2	Patient Care Bundles 02/2016 - 09/2015
1	Analgesia 01/2022
1	Pain Management 01/2022
1	Continuous Positive Airway Pressure 12/2021